Tuesday, January 28, 2014

PCR cyclers of the DNA Lab

Jeg har "døpt" den nye PCR-maskinen til McClintock. Barbara McClintock fikk Nobelprisen og sees av og til som en ikon av feministiske vitenskapsfolk. "Hun" er "slave" til Franklin. Litt fra wikipedia:
"Barbara McClintock (June 16, 1902 – September 2, 1992), was an American scientist and one of the world's most distinguished cytogeneticists, the 1983 Nobel Laureate in Physiology or Medicine

In the summer of 1944 at Cold Spring Harbor Laboratory, McClintock began systematic studies on the mechanisms of the mosaic color patterns of maize seed and the unstable inheritance of this mosaicism.

McClintock officially retired from her position at the Carnegie Institution in 1967, and was made a Distinguished Service Member of the Carnegie Institution of Washington.[36] This honor allowed her to continue working with graduate students and colleagues in the Cold Spring Harbor Laboratory as scientist emerita; she lived in the town.

Most notably, she received the Nobel Prize for Physiology or Medicine in 1983, the first woman to win that prize unshared, credited by the Nobel Foundation for discovering "mobile genetic elements"; it was more than 30 years after she initially described the phenomenon of controlling elements. She was compared to Gregor Mendel in terms of her scientific career by the Swedish Academy of Sciences when she was awarded the Prize.

McClintock died of natural causes in Huntington, New York, on September 2, 1992 at the age of 90; she never married or had children."

P.S.
"Rosalind Elsie Franklin (25 July 1920 – 16 April 1958) was a British biophysicist and X-ray crystallographer who made critical contributions to the understanding of the fine molecular structures of DNA (deoxyribonucleic acid), RNA, viruses, coal, and graphite. Her DNA work achieved the most fame because DNA plays an essential role in cell metabolism and genetics, and the discovery of its structure helped her co-workers understand how genetic information is passed from parents to their offspring.

Franklin is best known for her work on the X-ray diffraction images of DNA which led to the discovery of the DNA double helix. According to Francis Crick, her data was key to determining the structure to formulate Crick and Watson's 1953 model regarding the structure of DNA. Franklin's images of X-ray diffraction confirming the helical structure of DNA were shown to Watson without her approval or knowledge. This image and her accurate interpretation of the data provided valuable insight into the DNA structure, but Franklin's scientific contributions to the discovery of the double helix are often overlooked."

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