An interesting discussion - why do people use NCA?
A point on genetic markers was also made, by Andy:
"As far as using a single locus for inferring historical demography, it's fine to argue that it's unacceptable (and anyone with any knowledge of coalescent theory would agree), but again, as a practical matter, unless you are working on a fairly well-studied group, you are often stuck. Mitochondrial loci are easy to amplify and variable enough for intraspecific questions (too bad they are all linked), while primers for sufficiently variable nuclear loci are often unavailable without a lot of pilot work (and even if you do attempt to develop your own primers, you could come up with nothing useful)."
Two problems here:
- few markers known
- recombination
Can methods based on the Bayesian ever help us?
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